Well she is his love interest in the new movie, Pirates of the Caribbean: On Stranger Tides. There are big changes to this fourth part of the series, the is no more Keira Knightley and Orlando Bloom. Instead they are introducing Penelope Cruz are Captain Jack Sparrows new love interest.
The new movie is set to hit theaters in 2011... Can't wait!!!
Find out more about the movie by clicking here...
http://http://www.showbizspy.com/article/201928/penelope-cruz-to-play-johnny-depps-lover-in-fourth-pirates-of-the-caribbean-movie.html